Who’s Ready for Thanksgiving Day Football? Picks, Predictions & Key X-Factors
By Muhammad MubashirPublished On 01 Dec 2025
The Week 13 schedule for the 2025 NFL season begins with a great slate of Thanksgiving Day matchups, and we have you covered for what should be an exciting holiday. According to ESPN Research, the average over/under point total of 51.2 is the highest for Thanksgiving games over the past 40 seasons. Buckle up.
Ahead of the matchups, our NFL Nation reporters take you inside each locker room with key storylines and a look back at each team's history playing on Thanksgiving. ESPN Research provides optimistic stats for all six teams, along with betting nuggets to know. Plus, analytics writer Seth Walder makes bold predictions, while fantasy analyst Eric Moody shares fantasy football intel. We also have Football Power Index (FPI) game projections, and three analysts -- Pamela Maldonado, Moody and Walder -- give us final score picks for the three games.
Let's keep rolling with Bengals-Ravens on deck at 8:20 p.m. ET.
